Solubility as a limiting factor for expression of hepatitis A virus proteins in insect cell-baculovirus system
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منابع مشابه
Solubility as a limiting factor for expression of hepatitis A virus proteins in insect cell-baculovirus system
The use of recombinant proteins may represent an alternative model to inactivated vaccines against hepatitis A virus (HAV). The present study aimed to express the VP1 protein of HAV in baculovirus expression vector system (BEVS). The VP1 was expressed intracellularly with molecular mass of 35 kDa. The VP1 was detected both in the soluble fraction and in the insoluble fraction of the lysate. The...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2016
ISSN: 1678-8060,0074-0276
DOI: 10.1590/0074-02760160153